Professor Rupert Pearse

NIHR Professor of Intensive Care Medicine
Centre: Translational Medicine and Therapeutics
Email: r.pearse@qmul.ac.ukTelephone: +44(0) 20 3594 0351X: @rupert_pearse
Profile
ORCID iD: 0000-0002-4373-5934
Rupert Pearse graduated in 1996 from St George’s Hospital Medical School, London, UK. He also completed much of his clinical training in the south-west Thames region. His clinical duties are based on the busy Adult Critical Care Unit at the Royal London Hospital where he oversees the care of patients with critical illnesses of various causes. In 2006, Rupert was appointed Senior Lecturer in Intensive Care Medicine at Queen Mary University of London and was promoted to Professor in 2014. He is an active member of several national and international societies for anaesthesia and intensive care medicine. He leads the Critical Care and Perioperative Medicine Research Group. Rupert’s main research interest is in improving patient outcomes following major surgery, and has led numerous large multi-centre randomised trials, epidemiological studies and mixed-methods research projects in his field.
Research
Group members
Critical Care and Perioperative Medicine Research Group
Summary
My research is focused on improving the care pathway for patients before, during and after major surgery. This includes the study of risk factors for poor health, interventions during surgery which may improve patient outcomes, through to better ways to make decisions about surgical treatments together with patients. Increasingly, my work involves the care of patients who need surgical treatments in low and middle-income countries as well as high-income countries.
Publications
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Fowler AJ, Abbott TEF, Harrison EM et al. (2026). Long-term outcomes for patients at high risk of death after surgery in the UK: a retrospective cohort study. nameOfConference
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Thomas C, Pearse RM (2026). Corrigendum to ‘Socioeconomic deprivation and health inequity: independently associated with postoperative outcomes, and does this matter?’ (Br J Anaesth 2025; 135: 1141–3). nameOfConference
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Althonayan J, Fowler AJ, Allin B et al. (2025). Trends in Paediatric surgerical volume and associated mortality in England: a nationwide study over an eight year period. nameOfConference
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Dhesi JK, Partridge JSL, Strasser BC et al. (2025). Perioperative Medicine for Older People Undergoing Surgery Scale Up (POPS-SUp): study protocol. nameOfConference
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Thomas C, Pearse RM (2025). Socioeconomic deprivation and health inequity: independently associated with postoperative outcomes, and does this matter?. nameOfConference
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Dias P, Walshaw E, Flatau S et al. (2026). Penicillin allergy risk stratification tool for use by non‐allergists in the peri‐operative setting: an agreement study and qualitative process evaluation. nameOfConference
DOI: 10.1111/anae.16758
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Gordeev VS, Assefa E, Pearse R et al. (publicationYear). Health-related quality of life after emergency abdominal surgery. nameOfConference
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Silversides JA, Savic L, Hiller L et al. (publicationYear). Sugammadex or Neostigmine for prevention of post-operative pulmonary complications after major abdominal or thoracic surgery: study protocol for the SINFONIA (Sugammadex for preventioN oF pOst-operative pulmonary complIcAtions) randomised controlled superiority trial. nameOfConference
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Watson S-L, Fowler AJ, Pearse RM et al. (2025). The financial cost of postoperative complications: a prospective cohort study with linked health systems data. nameOfConference
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Giannas E, Patel A, Dias P et al. (2025). Perioperative management of renin–angiotensin system inhibitors in patients undergoing elective major noncardiac surgery: a mixed model investigation using systematic review, meta-analysis, multicentre service evaluation, and national survey. nameOfConference