Professor Zudin Puthucheary

Professor of Intensive Care Medicine
Centre: Critical Care and Perioperative Medicine Group
Email: z.puthucheary@qmul.ac.ukTelephone: +44(0) 20 3594 0319X: @Zudin_P
Profile
ORCID iD: 0000-0003-4267-1892
Zudin graduated from Nottingham University in 1997, and moved to London post MRCP in 2000. Following a 3-year stint in Sydney, he started his Respiratory training in Bristol, before completing his critical care training in London. His research focusses on acquired functional disability, and the use of metabolic, nutritional and exercise interventions to prevent and treat muscle. Zudin is a nationally elected Council member of the Intensive Care Society (UK) and a trustee for the National Confidential Enquiry into Patient Outcome and Death.
His work on acute muscle wasting has won awards from the European Society of Intensive Care Medicine , European Society of Anaesthesia, the British Thoracic Society, the Intensive Care Society, The American Society of Enteral and Parenteral Nutrition and Zudin was named a Global Rising Star by the Australia and New Zealand Intensive Care Society. He setup and chaired the UK National Post-Intensive Care Rehabilitation Collaborative until 2023, a multi-professional cross-disciplinary group focussing on rehabilitation and restitution of critical illness survivors.
Research
Critical Care and Perioperative Medicine Group
Our research is focused on both primary and secondary prevention of acquired functional disability following critical illness. We are primarily focused on physical disability- loss of muscle mass and the resultant decrease in physical activity, and attempts to modify this using metabolic, nutritional and exercise interventions. In addition, we seek to understand the patient population in terms of pre-existing multi-morbidity and frailty as important predisposing factors to disability, and as limiters to functional recovery. We continue to develop and refine tools for both identifying (biological signatures) and assessing (e.g the PICUPS tool) new functional disability.
Publications
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Puthucheary ZA, Van De Poll MCG (publicationYear). Is there really no harm in trying? The Cahill cycle and high-dose protein in critical illness. nameOfConference
QMRO: qmroHref -
Nazeer S, Mathieson G, Puthucheary Z et al. (2026). A qualitative study exploring critical care survivors’ and their clinicians’ shared experiences of navigating a fragmented care system. nameOfConference
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Alcaide M, Puthucheary Z, Prowle JR (2026). Macronutrient excess in critical illness: too much of a good thing?. nameOfConference
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Paul SN, Nessel I, Puthucheary Z et al. (publicationYear). Sepsis and the immunometabolic inflammatory response. nameOfConference
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Martindale R, Mundi MS, Waitzberg D et al. (2026). Integrating downstream mediators of Omega-3 fatty acids into enteral nutrition for improved patient care: An expert panel consensus. nameOfConference
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Eggmann S, Parry SM, Broadley T et al. (2025). The intensive care medicine research agenda for the management of ICU acquired weakness: a multinational, interprofessional perspective. nameOfConference
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Parry SM, Soh S-E, Morris PE et al. (2026). “From the moment I started standing again, I was worried about falls”: fear of falling in intensive care unit survivors over 12 months. nameOfConference
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Matsumoto K, Fazzini B, Malcolm H et al. (2025). Factors influencing multidisciplinary clinical decision-making in the critical care unit: a systematic review and mixed-methods meta-synthesis. nameOfConference
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Nessel I, Paul SN (2025). Unveiling Organ Failure in the Critically Ill: Insights through the Metabolite Lens. nameOfConference
Collaborators
Internal
- Dr John Prowle
- Prof Gareth Ackland
- Prof Andrew Prendegast
- Prof Aylin Basan
- Prof Sian Henson
- Prof Adina Michael-Titus
External
International:
- Profs Linda Denehey and Sue Berney (University of Melbourne)
- Prof Stephen Olde Damick (University of Maastricht)
- Sepsis and Critical Illness Research Centre (University of Florida)
- Dr Louise Thwaites (Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh, Vietnam)
National:
- Medical Research Council/Arthritis Research UK Centre of excellence for musculoskeletal ageing research (University of Nottingham)
- Centre of Human and Aerospace Physiological Sciences (Kings College London)
- Centre for Human Health and Performance (University College London)
Disclosures
- GlaxoSmithKline - Specialist Advisory Board for muscle wasting in critical illness
- Fresunius Kabi - Specialist Advisory Board for functional recovery post-critical illness
- Lyric Pharmaceuticals - Consultant
- Faraday Pharmaceuticals - Consultant
- Nestle - Specialist Advisory Board for muscle wasting in critical illness
- Nutricia - Specialist Advisory Board for mitochondrial dysfunction in critical illness
- Bioage - Consultant