Professor Shafaq Sikandar

Professor of Sensory Neurophysiology
Centre: Experimental Medicine and Rheumatology
Email: s.sikandar@qmul.ac.uk
Profile
ORCID iD: 0000-0002-6010-5205
Professor Shafaq Sikandar is the group leader of the Sensory Neurophysiology lab at the William Harvey Research Institute. Her research training was based on rodent and human models to study the neurophysiology of pain. Shafaq’s PhD training was in the Pharmacology department of University College London, and she continued postdoctoral training in the Anaesthesiology department of University of California San Diego and in the Wolfson Institute of Biomedical Research of UCL. In 2018 she was awarded a Versus Arthritis fellowship and appointed lecturer in sensory biology in the Centre for Experimental Medicine and Rheumatology.
The Sensory Neurophysiology lab researches neuronal mechanisms underlying the transition from acute to chronic pain, with a focus on musculoskeletal pain and neuro-immune interactions. We use in vivo and back translational approaches with mouse models in combination with molecular biology. Clinical studies are focussed on patients with post-surgical pain, arthritis, cancer pain and fibromyalgia.
Shafaq teaches on BSc modules Repair & regeneration (BMD361) / Disconnected pathways (ICM6013) and is the FMD Equality Diversity and Inclusion Lead for Communications and Engagement.
Research
Group members
Dr Sara Caxaria (PDRA); Dr Alice Fuller (PDRA); Ms Sabah Bharde (PhD); Dr Brian Herath (PhD); Ms Romy Evans (PhD); Ms Niloofar Ketahi (PhD); Ms Petek Celik (Technician)
Publications
-
Sikandar S (publicationYear). Patient perspectives like mine are missing from parliament’s assisted dying discussions. nameOfConference
DOI: 10.1136/bmj.s64
QMRO: qmroHref -
Hestehave S, Florea R, Singleton S et al. (2025). Analgesia through FKBP51 inhibition at disease onset confers lasting relief from sensory and emotional chronic pain symptoms. nameOfConference
-
Sikandar S, Ackland GL (2025). Chronic pain: a modifiable target to reduce perioperative cardiovascular morbidity. nameOfConference
-
Haroun R, Gossage SJ, Iseppon F et al. (2024). Novel therapies for cancer-induced bone pain. nameOfConference
-
Eldridge S, Dajas-Bailador F, Chapman V et al. (2024). POS0217 AGRIN HAS A DIRECT ANALGESIC EFFECT IN OSTEOARTHRITIS MODELS.. nameOfConference
QMRO: qmroHref -
Bai Z, Bartelo N, Aslam M et al. (2024). Synovial fibroblast gene expression is associated with sensory nerve growth and pain in rheumatoid arthritis. nameOfConference
-
Dajas-Bailador F, Chapman V, Lucci C et al. (2024). 069 INTRA-ARTICULAR ADMINISTRATION OF AGRIN INDUCES RAPID AND SUSTAINED PAIN RELIEF IN OSTEOARTHRITIS. nameOfConference
-
Bharde S, Caxaria S, Celik P et al. (2024). 754 Sex Differences in a Murine Model of Osteoarthritis. nameOfConference
-
Haroun R, Gossage SJ, Luiz AP et al. (2023). Chemogenetic Silencing of NaV1.8-Positive Sensory Neurons Reverses Chronic Neuropathic and Bone Cancer Pain in FLEx PSAM4-GlyR Mice. nameOfConference
QMRO: qmroHref -
Fuller AM, Bharde S, Sikandar S (publicationYear). The mechanisms and management of persistent postsurgical pain. nameOfConference
QMRO: qmroHref
Sponsors
We are grateful to our generous funders:
Collaborators
Internal
- Dr Sibtain Anwar (WHRI)
- Dr Mathieu Benoit-Voisin (WHRI)
- Prof Myles Lewis (WHRI)
- Prof Costantino Pitzalis (WHRI)
External
- Prof John Wood (UCL)
- Prof Guilherme Barros (UNESP)
Disclosures
No disclosures.