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Wolfson Institute of Population Health

Dr Isabelle Foote

Isabelle

Lecturer in Genomics and Ageing

Email: i.foote@qmul.ac.uk

Profile

I am a Lecturer in Genomics and Ageing based in the Centre for Preventive Neurology (CPN) and the Academic Centre for Healthy Ageing (ACHA). I am currently undertaking a Wellcome Trust Early Career Award exploring the mechanisms of accelerated ageing in diverse populations and how this leads to increased risk of neurodegenerative diseases.

I co-lead the Prevention Working Group of the Deep Dementia Phenotyping (DEMON) Network, an international network of researchers and industrial partners with a shared interest in applying data science and AI methods to dementia research.

Previously, I completed my undergraduate nursing studies at the University of Birmingham, before graduating in Neuroscience from King’s College London. I then undertook a PhD in Epidemiology at QMUL, which focused on the genetics of modifiable risk factors for dementia. I then moved to the University of Colorado Boulder where I undertook postdoctoral training in statistical genetics at the Institute for Behavioural Genetics before returning to QMUL for my current role. 

Research

Research Interests:

My research mainly focuses on applying and developing multivariate genomic methods to explore how modifiable risk factors lead to neurodegeneration and poor brain health later in life. I am particularly interested in modelling the genetic architecture of complex age-related phenotypes, such as frailty and resilience, to identify ways to prevent cognitive decline and maintain brain health through public health interventions or the development of pharmacological therapies.

I am passionate about reducing inequalities in healthcare by conducting more inclusive research across diverse populations and engaging the public in genetic epidemiology and ageing research. 

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