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Dr Suzanne Elridge

Discover how Dr Suzanne Elridge navigated her journey to ReFleks and the community power that she harnessed.

Your Journey

My journey began in engineering, working on projects centred around joint prostheses. While it was exciting to refine mechanical solutions, I found myself asking a deeper question — why do joints fail in the first place? I wanted to address the root cause of degeneration rather than improve the end-stage intervention. That motivation led me to join Professor Francesco Dell’Accio’s lab at, where I transitioned from engineering into cartilage molecular biology.

During my PhD, I discovered the critical role of a protein called Agrin in maintaining cartilage health. This insight revealed a new biological mechanism that could protect and repair cartilage tissue. Together with Francesco, I co-founded ReFleks to develop Agrin as a therapeutic for osteoarthritis.

Building ReFleks has been a steep but rewarding learning curve — balancing scientific integrity with the realities of regulation, IP, and funding. It’s been a true translation journey: from engineering principles to biological insight, and ultimately towards a therapy that could make a real difference for patients.

 

The Power of Community

The community at Queen Mary University of London has been central to my development as both a scientist and entrepreneur. Within the School of Engineering and Materials Science (SEMS), I built the analytical and problem-solving mindset that still underpins my work. Working with colleagues across the William Harvey Research Institute and the Blizard Institute - in particular the Centre for Bone and Joint Health - have provided an inspiring and supportive environment for translational research.

The support of Arthritis UK and Queen Mary Innovation has been equally vital — offering mentorship, resources, and opportunities to bridge the gap between academia and enterprise. This network embodies the spirit of “Together We Build”: a community where engineers, clinicians, and scientists work side by side to turn discoveries into therapies. ReFleks is, in many ways, the outcome of that shared vision.

 

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